Anniversary Collection:
35 Years of STEM CELLS

Jan A. Nolta

To mark the 35th anniversary of STEM CELLS, we looked at the top cited articles from the past 34 volumes and invited the authors of these influential articles to provide an update, commenting on the current state of the field, for this special celebratory collection.

Read the Editor’s Note here.

Anniversary Collection: 35 Years of STEM CELLS

Update: Mesenchymal Stem/Stromal Cells: Variability of Tissue Sources and Ex Vivo Manufacturing Protocols
Karen Bieback, Adriana Torres Crigna, and Agnese Fiori

Comparative Analysis of Mesenchymal Stem Cells from Bone Marrow, Umbilical Cord Blood, or Adipose Tissue
Susanne Kern, Hermann Eichler, Johannes Stoeve, Harald Klüter, and Karen Bieback

Update: Wharton’s Jelly Mesenchymal Stem Cells: Biological Characteristics and Therapeutic Potential in Regenerative Medicine
Hwai-Shi Wang

Mesenchymal Stem Cells in the Wharton’s Jelly of the Human Umbilical Cord
Hwai-Shi Wang, Shih-Chieh Hung, Shu-Tine Peng, Chun-Chieh Huang, Hung-Mu Wei, Yi-Jhih Guo, Yu-Show Fu, Mei-Chun Lai, and Chin-Chang Chen

Update: Homing of Mesenchymal Stem Cells
Oksana Kehoe, James Fox and Jim Middleton

Concise Review: Mesenchymal Stem Cells: Their Phenotype, Differentiation Capacity, Immunological Features, and Potential for Homing
Giselle Chamberlain, James Fox, Brian Ashton, and Jim Middleton

Update: Beginning of an Unresolved Debate: Should Mesenchymal Stem Cells Be Expanded at Low Density to Preserve Early Progenitors?
Ichiro Sekiya and Darwin J. Prockop

Expansion of Human Adult Stem Cells from Bone Marrow Stroma: Conditions that Maximize the Yields of Early Progenitors and Evaluate Their Quality
Ichiro Sekiya, Benjamin L. Larson, Jason R. Smith, Radhika Pochampally, Jian-Guo Cui, and Darwin J. Prockop

Update: Retrospective on Human Adipose-Derived Cell Immunophenotype
Jeffrey M. Gimble

Immunophenotype of Human Adipose-Derived Cells: Temporal Changes in Stromal-Associated and Stem Cell–Associated Markers
James B. Mitchell, Kevin McIntosh, Sanjin Zvonic, Sara Garrett, Z. Elizabeth Floyd, Amy Kloster, Yuan Di Halvorsen, Robert W. Storms, Brian Goh, Gail Kilroy, Xiying Wu, and Jeffrey M. Gimble

Update: Mesenchymal Stem Cells in Wound Healing: Challenges in Translation
Yaojiong Wu and Edward E. Tredget

Mesenchymal Stem Cells Enhance Wound Healing Through Differentiation and Angiogenesis
Yaojiong Wu, Liwen Chen, Paul G. Scott, and Edward E. Tredget

Update: Bone Marrow Stromal Stem Cells (Skeletal Stem Cells)
Stan Gronthos, Sergei A. Kuznetsov, Mara Riminucci, and Pamela G. Robey

Bone Marrow Stromal Stem Cells: Nature, Biology, and Potential Applications
Paolo Bianco, Mara Riminucci, Stan Gronthos, and Pamela Gehron Robey

Update: A Change in Hypotheses: Mesenchymal Stem/Stromal Cells Produce Therapeutic Effects Without Engrafting
Donald G. Phinney and Darwin J. Prockop

Concise Review: Mesenchymal Stem/Multipotent Stromal Cells: The State of Transdifferentiation and Modes of Tissue Repair—Current Views
Donald G. Phinney and Darwin J. Prockop

Press Releases

Stem Cells May Help Improve Corneal Wound Healing

Stem Cell Treatment Has Potential to Help Parkinson’s Disease Unexpected Brain Area

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Article Scans

Video Highlights

Video abstract from Drs. Banerjee, Surendran, Bharti, Morishita, Varshney, and Pal on their recently published STEM CELLS paper entitled, "Long non-coding RNA RP11-380D23.2 drives distal-proximal patterning of the lung by regulating PITX2 expression." Read the paper here.

Video abstract from Drs. Sayed, Ospino, Himmati, Lee, Chanda, Mocarski, and Cooke on their recently published STEM CELLS paper entitled, "Retinoic Acid Inducible Gene 1 Protein (RIG1)-like Receptor Pathway is Required for Efficient Nuclear Reprogramming." Read the paper here.

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