STEM CELLS Translational Medicine Highlights

Anthony Atala
STEM CELLS Translational Medicine

STEM CELLS Translational Medicine Highlights is a special collection of significant articles reflecting both the scope and promise of the field, as well as the challenges that lie ahead. These articles highlight a range of cell types, including newly identified progenitor cells, embryonic cells, and induced pluripotent stem cells (iPSCs). We invite you to explore this compilation and hope that it sheds new light on discoveries that could lead to new breakthrough therapies.

Read the Editor's Note here.

Pluripotent Stem Cells

A Human Pluripotent Stem Cell Model of Facioscapulohumeral Muscular Dystrophy-Affected Skeletal Muscles
Leslie Caron, Devaki Kher, Kian Leong Lee, Robert Mckernan, Biljana Dumevska, Alejandro Hidalgo, Jia Li, Henry Yang, Heather Main, Giulia Ferri, Lisa M. Petek, Lorenz Poellinger, Daniel G. Miller, Davide Gabellini, Uli Schmidt

Genetic Correction of Induced Pluripotent Stem Cells From a Deaf Patient With MYO7A Mutation Results in Morphologic and Functional Recovery of the Derived Hair Cell-Like Cells
Zi-Hua Tang, Jia-Rong Chen, Jing Zheng, Hao-Song Shi, Jie Ding, Xiao-Dan Qian, Cui Zhang, Jian-Ling Chen, Cui-Cui Wang, Liang Li, Jun-Zhen Chen, Shan-Kai Yin, Tao-Sheng Huang, Ping Chen, Min-Xin Guan, Jin-Fu Wang

Human Induced Pluripotent Stem Cells Differentiate Into Functional Mesenchymal Stem Cells and Repair Bone Defects
Dmitriy Sheyn, Shiran Ben-David, Galina Shapiro, Sandra De Mel, Maxim Bez, Loren Ornelas, Anais Sahabian, Dhruv Sareen, Xiaoyu Da, Gadi Pelled, Wafa Tawackoli, Zhenqiu Liu, Dan Gazit, Zulma Gazit 

Robust Differentiation of mRNA-Reprogrammed Human Induced Pluripotent Stem Cells Toward a Retinal Lineage
Akshayalakshmi Sridhar, Sarah K. Ohlemacher, Kirstin B. Langer, Jason S. Meyer

Tissue-Specific Progenitor and Stem Cells

Expansion and Hepatic Differentiation of Adult Blood-Derived CD34+ Progenitor Cells and Promotion of Liver Regeneration After Acute Injury
Min Hu, Shaowei Li, Siddharthmenon, Bo Liu, Michael S. Hu, Michael T. Longaker, H. Peter Lorenz

Grafted Subventricular Zone Neural Stem Cells Display Robust Engraftment and Similar Differentiation Properties and Form New Neurogenic Niches in the Young and Aged Hippocampus
Ashok K. Shetty, Bharathi Hattiangady

Human Cartilage-Derived Progenitor Cells From Committed Chondrocytes for Efficient Cartilage Repair and Regeneration
Yangzi Jiang, Youzhi Cai, Wei Zhang, Zi Yin, Changchang Hu, Tong Tong, Ping Lu, Shufang Zhang, Dante Neculai, Rocky S. Tuan, Hong Wei Ouyang

Protocols and Manufacturing for Cell-Based Therapies

Alginate-Encapsulation for the Improved Hypothermic Preservation of Human Adipose-Derived Stem Cells
Stephen Swioklo, Andrei Constantinescu, Che J. Connon

Tissue Engineering and Regenerative Medicine

Human Cortical Neural Stem Cells Expressing Insulin-Like Growth Factor-I: A Novel Cellular Therapy for Alzheimer’s Disease
Lisa M. Mcginley, Erika Sims, J. Simon Lunn, Osama N. Kashlan, Kevin S. Chen, Elizabeth S. Bruno, Crystal M. Pacut, Tom Hazel, Karl Johe, Stacey A. Sakowski, Eva L. Feldman 

Tumor-Free Transplantation of Patient-Derived Induced Pluripotent Stem Cell Progeny for Customized Islet Regeneration
Moustafa M. El Khatib, Seiga Ohmine,Egon J. Jacobus, Jason M. Tonne, Salma G. Morsy,A Sara J. Holditch, Claire A. Schreiber, Koji Uetsuka, Noemi Fusaki, Dennis A. Wigle, Andre Terzic, Yogish C. Kudva, Yasuhiro Ikeda

Press Releases

Scientists Identify Molecule That May Help Aid Kidney Repair

Dr. Philippe Lysy’s Search in New Sources for Insulin-Producing Cells Earns Him the 2017 SCTM Young Investigator Award

Study Shows How Growth Factor Aids Stem Cells’ Ability to Regenerate Damaged Teeth

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Featured Video

Video abstract on the recently published STEM CELLS Translational Medicine Perspective 'Role of Nursing Competencies for Accelerating Clinical Trials in Stem Cell Clinics.' Read the Perspective here.

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