STEM CELLS Information for Authors



Mission and Focus

STEM CELLS, a peer reviewed journal published monthly, provides a forum for prompt publication of original investigative papers and concise reviews. STEM CELLS is read and written by clinical and basic scientists whose expertise encompasses the rapidly expanding fields of stem and progenitor cell biology.

STEM CELLS welcomes original articles and concise reviews describing basic laboratory investigations of stem cells and the translation of their clinical aspects of characterization and manipulation from the bench to patient care. The journal covers all aspects of stem cells embryonic stem cells/induced pluripotent stem cells; tissue-specific stem cells; stem cell technology: epigenetics, genomics, proteomics, and metabonomics; cancer stem cells; translational and clinical research; and regenerative medicine.

Disclaimer

While the co-publishers, AlphaMed Press and Wiley, and Editorial Board make every effort to see that no inaccurate or misleading data, opinions, or statements appear in the Journal, they wish to state that the data and opinions in the articles and advertisements herein are the responsibility of the contributor or advertiser concerned. Accordingly, the co-publishers, the Editorial Board, and their respective employees, officers and agents accept no liability whatsoever for the consequences of any inaccurate or misleading data, opinion, or statement.

Scope

STEM CELLS covers:

  • Embryonic Stem Cells/Induced Pluripotent Stem (iPS) Cells
    • Signaling pathways/factors regulating and/or initiating ESC/iPS cells pluripotency and differentiation
    • Derivation and organization of primitive, early structures with or without tissue specificity
  • Tissue-Specific Stem Cells
    • Regulation of and pathways that govern stem cell self-renewal and/or differentiation
    • Cellular interactions and signaling pathways necessary for tissue specificity
    • Molecules and signaling pathways that modulate homing or mobilization of tissue-specific stem/progenitor cells
    • Functional properties of tissue-specific and progenitor cells
    • Improving engraftment for efficient and less costly cellular therapy for adult stem cells
    • Understanding and avoiding teratoma formation
  • Stem Cell Technology: Epigenetics, Genomics, Proteomics, and Metabonomics
    • Mutagenesis and epigenetic influences
    • Surveys of gene and/or protein expression with a link to structure or function
    • Quantitative measurements of the dynamic multiparametric metabolic response of living systems to pathophysiological stimuli or genetic modification
    • Prediction of the outcome (efficacy or toxicity) of a drug or xenobiotic intervention in an individual based on a mathematical model of preintervention metabolite signatures
  • Cancer Stem Cells
    • Cellular origin of cancer stem cells
    • Genetic constraints, including epigenetic modifications, that influence growth process
    • The cancer stem cell niche, and cancer stem cells as therapeutic targets
    • Mathematical models of cancer cell evolution and mechanisms of survival
  • Translational and Clinical Research
    • Studies describing new model systems with potential for drug development
    • Translation into pharmaceutical, clinical or practical findings
  • Regenerative Medicine
    • Potential applications for stem cell-based strategies in pathological conditions
    • Tissue engineering and characterization of engineered tissues
    • Medical device and artificial organ development
    • Stem cell transplantation and technologies that will maintain, improve or restore the function of diseased organs
    • Gene therapies for inherited diseases

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Editorial Policies

STEM CELLS Editorial Policies follow the recommendations of the International Committee of Medical Journal Editors (ICMJE), the World Association of Medical Editors (WAME), and the Committee on Publication Ethics (COPE) for guidance on policies and procedures related to publication ethics. The policies for STEM CELLS have been adopted from those three advisory bodies and, where necessary, modified and tailored to meet the specific content, audiences, and aims of STEM CELLS.

Submission of a manuscript is predicated on the explicit understanding that it represents original work not previously published (with the exception of abstracts) and not being considered elsewhere for publication. As part of our commitment to the scientific community to uphold a high standard of publication ethics, STEM CELLS uses CrossCheck powered by iThenticate software to check the originality of manuscripts. For more information on CrossCheck visit their website at http://www.crossref.org/crosscheck/index.html.  Additionally, all accepted manuscripts will undergo a final figure review and screening process by the Science Editors before publication.

Further, it is understood that all authors listed on a manuscript have agreed to its submission. Authors submitting a manuscript do so with the understanding that if it is accepted for publication, the copyright, including the right to reproduce the article in all forms and media, shall be assigned exclusively to the copyright holder, AlphaMed Press. It is the corresponding author's responsibility to obtain written permission to reproduce illustrations, tables, etc., from other publications.

Questions related to this policy should be directed to the editors at Editors@stemcellstm.com.

Conduct Policy

As the first journal devoted to the fast-paced area of stem cells and regenerative medicine, STEM CELLS remains in the top tier of peer-reviewed monthly journals for this discipline. This mission requires ongoing, scrupulous attention to the quality and integrity of the Journal's publications, and irreproachable conduct on the part of its authors, reviewers, and editors. In pursuit of this goal, STEM CELLS has adopted a Conduct Policy that reflects and supports the Journal's unwavering commitment to the quality and integrity of work it publishes.

The Conduct Policy outlines the standards of professional behavior expected of authors, reviewers, and editors, and addresses the Journal's policy for handling potential instances of misconduct.

STEM CELLS is a member of, and subscribes to the principles of, the Committee on Publication Ethics (COPE) www.publicationethics.org.

For any questions or concerns regarding the Conduct Policy, please contact the editorial office for STEM CELLS(EditorialOffice@stemcells.com).

Author Responsibilities

It is the responsibility of submitting authors to ensure that the data and work represented in their manuscript are accurately presented at the time of submission. For all submitted papers, accurate representation includes the submission of only original and unpublished material, proper acknowledgment of all author contributions, properly credited references and resources, and presentation of all relevant data and results in their true, unaltered form. The Journal requires a statement disclosing any financial relationship that is relevant to the work, and that might be perceived as a conflict of interest.

In addition, if manuscript content is based on scientific research, then that research is required not only to meet accepted scientific standards, but also to adhere to any applicable legal and ethical requirements regarding informed consent of human subject and standards for use of experimental animals.

Authorship & Contributions

STEM CELLS adheres to the guidelines on authorship established by the International Committee of Medical Journal Editors (ICMJE) statement on Authorship and Contribution available at http://www.icmje.org/recommendations/browse/roles-and-responsibilities/defining-the-role-of-authors-and-contributors.html.
The corresponding author must have obtained permission from all authors for the submission of each version of the paper and for any change in authorship. Authorship should be limited to those who have contributed substantially to the work. The nature of the contribution of every author should be made clear. Each author should have participated sufficiently in the work to take public responsibility for the content.

If an article has been substantially written by a contracted writer not named in the byline, this fact needs to be noted in the Acknowledgments section of the manuscript. In addition, all other contributors who do not meet sufficient criteria for authorship should also be noted in the Acknowledgments section.

STEM CELLS conflict of interest policy requires complete transparency between the Journal's editors, the investigator-author(s), and any contracted writer(s). The Journal requires identification of the contracted writer(s) and clarification of their role. As part of this policy, the Journal requires that the Corresponding Author stipulate his/her principal authorship and responsibility for the content of the paper. The policy further requires that any and all correspondence from manuscript submission onward must be conducted exclusively by and between the Corresponding Author and the Journal editors.

Sponsorship

Authorship entails both accountability and independence. A submitted manuscript is the intellectual property of its authors, not the study's sponsor (e.g., a pharmaceutical company or contract research organization). The Journal will not review or publish articles based on studies that are conducted under conditions that allow the sponsor to have sole control of the data or to withhold publication. We encourage investigators to use the revised International Council of Medical Journal Editors (ICMJE) requirements on publication ethics to guide the negotiation of research contracts. Those contracts should give the researchers a substantial say in trial design, access to the raw data, responsibility for data analysis and interpretation, and the right to publish; these are the hallmarks of scholarly independence and, ultimately, academic freedom. By enforcing adherence to these requirements, we can as editors endeavor to assure our readers that the authors of an article have had a meaningful and truly independent role in the study that bears their names. The authors, therefore, will stand behind the published results, and so can the Journal.

Conflict of Interest and Financial Disclosure 

Upon submission, authors are required to disclose any financial relationships that may present a potential conflict of interest in the communication of nonbiased scientific information. The purpose of the Potential Conflict of Interest and Financial Disclosure Form is to fully inform the Journal's editors, reviewers, and readers of the existence of any financial relationships that may be pertinent to the article and thus ensure full transparency of the peer-review and publication processes.

It is the policy of STEM CELLS to ensure fair balance, independence, objectivity, and scientific rigor in all of its educational activities through the disclosure of financial interests and other relationships. Additionally, STEM CELLS abides by the policy of the Accreditation Council for Continuing Medical Education (ACCME) stating that commercial support must be acknowledged and that all persons who affect the content of an educational activity regarding the products or services of a commercial interest must disclose any financial relationships with that commercial interest.

To this end, the corresponding author and all co-authors for each article are required by STEM CELLS to complete a Potential Conflict of Interest and Financial Disclosure Form to disclose any financial commitment or obligation occurring within the last 12 months relevant to the subject matter of the article submitted. Additional relationships that might be considered competing interests, such as holding equity or paid consultancy, patent rights, etc., must also be stated.

All information concerning potential conflicts of interest will be revealed to the peer reviewers and thereafter kept confidential (and on file by the Journal's editorial office). The Editorial Office will work with the corresponding author to formulate a disclosure statement for publication, should the manuscript be accepted. Any potential conflicts of interest found will be reviewed by the Editorial Board with the ad hoc assistance of external reviewers and resolved prior to publication.

Editors and Reviewers

Editors and reviewers are required to disclose financial interests or relationships and answer the same questions as authors. Reviewers are asked to disclose financial information when accepting a review assignment.

Defining a Conflict of Interest

A conflict of interest exists when individuals have both a financial relationship with a commercial interest and the opportunity to affect the content of an article about the product or services of that commercial interest. Nothing in this policy statement should be regarded as creating a presumption of impropriety in the existence of financial relationships. Rather, it is the purpose of this policy to inform the peer reviewers, and subsequently the readers, of the existence of financial relationships pertinent to the article in the interest of full transparency in the peer review and publication processes.

Criteria for Disclosure of Conflicts of Interest

A commercial interest is defined as any entity producing, marketing, re-selling, or distributing health care goods or services consumed by, or used on, patients (not including providers of clinical services). Relationships with governmental agencies (e.g., the NIH), do not have to be disclosed. In addition, honoraria (or fee-for-service) or consulting funds from a Continuing Medical Education CME provider do not need to be disclosed. In addition to personal disclosure, you must disclose any financial relationships your spouse or life partner has with applicable commercial interests.

Authors who identify contracted writers should disclose the funding source. Contracted medical/science writers are also required to submit a Potential Conflict of Interest and Financial Disclosure Form.

Misconduct

Instances involving potential author misconduct can relate to either submitted or published manuscripts. The Journal's author misconduct policy does not apply to "honest" mistakes of judgment or interpretation, which may be resolved through subsequent publication of an erratum.

Examples of potential author misconduct may include, but are not limited to, the following circumstances:

  • Falsifying, manipulating, or omitting data or results, images, or any other materials, processes, or content, such that the research record is not faithfully presented and preserved.
  • Fabricating data or results
  • Plagiarizing or otherwise not appropriately crediting the work of others or oneself (includes ideas, processes, words, results, etc.)
  • Misappropriating the data or results of others and representing them as one's own
  • Submitting or publishing the same, or essentially unchanged, material in more than one publication
  • Using published images, charts, tables, etc. without first obtaining appropriate permissions
  • Removing or failing to include or properly credit a contributing author or writer, including a paid professional writer.
  • Inappropriately assigning author status to a "guest" author or "ghostwriter" whose contributions do not meet the authorship criteria as defined by the International Committee of Medical Journal Editors (ICMJE; www.ICMJE.com); such contributions should be noted instead in the "Acknowledgments" section in the manuscript.
  • Failing to appropriately disclose any potential conflicts of interest
  • Failing to abide by applicable legal and ethical standards regarding the treatment of research subjects

Potential Author Misconduct Notification and Investigation

Notification of Potential Misconduct/Response to Notifying Party

When a potential breach of conduct is brought to the Journal's attention, the Journal will contact the notifying party to acknowledge receipt of the notification. Unless the notifying party has been personally affected by the alleged misconduct, correspondence with that individual will end with the acknowledgment that notification of the concern has been received.
Potential author misconduct may also be discovered by the Journal's staff, editors and/or reviewers, in which case the same investigative process applies.

Misconduct Notification and Investigation

Following a receipt of notification of potential author misconduct, the Journal will initiate a preliminary investigation in order to determine whether a formal investigation is warranted. In this phase of the investigation, published and submitted manuscripts, manuscript reviews, and editorial decisions will be evaluated as appropriate. Input will be sought from all individuals affected by the alleged misconduct. If the evidence found is substantial enough to warrant further investigation, the Journal will notify the corresponding author of the manuscript in question and request a full explanation. Should the corresponding author not respond (or not respond in a timely manner) or provide an inadequate or otherwise unsatisfactory response, the Journal will contact the corresponding author's institution and/or co-authors.

If the potential misconduct involves a work published elsewhere, the Journal may also contact that publication. Should the potential misconduct involve specific scientific research, the Journal may also contact the institution where the research was conducted in order to further investigate the accuracy, authenticity, and legitimacy of the published data and results. Lastly, the Journal may also request the assistance of the U.S. Department of Health and Human Services Office of Research Integrity.

During the investigative process, the Journal will follow the guidelines and requirements outlined by the Committee on Publication Ethics (COPE) and the ICMJE to identify any misconduct and fairly gauge its severity. These references are available online at http://publicationethics.org/resources/flowcharts and at http://www.icmje.org.


Sanctions

Potential instances of author misconduct will be investigated and considered on a case-by-case basis. Should misconduct be established or admitted, the Journal will proceed with sanctions as deemed commensurate with the severity of the misconduct committed. All decisions regarding sanctions or notices of misconduct will be reviewed by the senior editorial board of STEM CELLS to seek their advice and agreement with the planned action.

Sanctions are applied at the discretion of the Editor-in-Chief, the senior editorial board, and the publisher and may vary based on the severity of the misconduct and whether the manuscript in question was submitted or published.

Appropriate sanctions for author misconduct may include, but are not limited to, the following:

  • Publication of an erratum or Statement of Concern by the Journal Editors
  • Rejection of the manuscript or retraction of the publication in which the misconduct was committed
  • A letter of notice of sanctions to the author(s)
  • A letter of notice to the author's institution and/or the institution where the study was conducted
  • Prohibition of further submissions to or publications in the Journal by the offending author for a period of time to be determined by the Editor-in-Chief

Once the decision on sanctions has been determined, the Journal will notify the author.


Editors and Reviewers

Editors and reviewers are also required to abide by the Conduct Policy and therefore should be familiar with the Journal's policy regarding conflicts of interest and should be prepared to recuse themselves from any situation that would potentially place them in violation of that policy.

In addition to knowing when to recuse themselves from a review, editors and reviewers should also keep in mind that all information submitted for review purposes is confidential in nature and should be treated as such.

Recusal of Editors and Reviewers

In order to provide authors with a fair and unbiased review process, Editors (Senior and Associate Editors and Lead Reviewers), and reviewers are required to recuse themselves from the review of a manuscript when faced with a potential conflict of interest. Examples of situations that would require recusal on behalf of an editor or reviewer include but are not limited to:

  • An editor or reviewer is the spouse, domestic partner, parent, child, sibling, or other family member of an author on the manuscript in review.
  • An editor or reviewer is involved in research collaboration with an author on the manuscript in review.
  • An editor or reviewer is under the employ of, or otherwise works at, the same institution as an author on the manuscript in review.
  • An editor or reviewer has a strong intellectual bias either for or against the position taken by the author.
  • An editor or reviewer has a financial interest in an agent or device relevant to the study, or has a financial relationship with a commercial sponsor of the study in question.
  • In addition to self-recusal, editors and reviewers are also required to recuse themselves from the review of a manuscript when requested to do so by the Editor-in-Chief.

Questions regarding the recusal policy may be directed to Editors@stemcells.com.

Misconduct of Editorial Board Members

STEM CELLS holds its Editorial Board members, as ambassadors of the Journal, to the same high standards of ethical conduct as are expected for authors. Editorial Board members who act as reviewers must honor the confidentiality of all information in the reviewer packet.

If an Editorial Board member is the subject of an accusation of misconduct as an author, reviewer, or Editorial Board member, the accusation will be referred to the Journal's executive office and Editor-in-Chief for review and appropriate action.


Ethical Guidelines

Internal Review Board Guidelines for Medical Research Involving Human Subjects

A goal of STEM CELLS is to ensure that all articles reflect work that is morally acceptable. Authors must abide by the rules of a formally constituted research ethics committee, and/or their Institutional Review Board (IRB), and the tenets of the World Medical Association's Declaration of Helsinki. Ethical aspects of any submitted work that involves human participants, including research, audit, and sometimes debate, should be appraised. Policy on these issues has been developed with the help and advice of the Senior Leadership Ethics Committee and its key elements are explained here.

To facilitate an ethics appraisal, every research article submitted to STEM CELLS is required to include a statement that the authors obtained ethics approval (or a statement that it was not required), including the name of the ethics committee or Institutional Review Board, the number/ID of the approvals, and a statement that participants gave informed consent before taking part. This applies to all types of articles, including trials involving active interventions, non-intervention studies, and audits.

All trials involving an active intervention, either treatment or diagnostic, must be accompanied by a statement of approval by the local IRB or similar ethics committee, and a statement guaranteeing that all patients gave written informed consent.

Non-intervention studies should include a statement verifying that the study has been approved, or determined exempt, by an independent ethics committee, that informed consent has been obtained even if documentation of informed consent has been waived, and that the information contained is kept confidential and all identifiers have been removed prior to submission for publication.

We believe that studies referred to as audits also need consideration of an ethics committee. The distinction between "research," which investigates what should be done, and "audit," which investigates whether it is being done, may be unclear. However, the assumption that audit or analysis of previously collected data is not subject to ethical analysis cannot be justified.

Investigators are invited to explain in detail how the ethics of their study were justified. We also welcome the submission of any informational sheets that were provided to participants. If such detail does not easily fit into the manuscript, this information should be provided in the cover letter or uploaded as a supplemental file when submitting the article. This detailed information may not be published, but we may make it available to peer reviewers and editorial committees. Peer reviewers are asked to consider and comment on the ethics of submitted work.

Animal Welfare

Manuscripts reporting on studies that involve experiments with animals must include a statement verifying that care of animals was in accordance with institutional guidelines.

Guidelines for Stem Cell Research

Research with embryonic stem cells should adhere to the guidelines established by the National Academy of Sciences, as published in the National Academies Press, at http://nap.edu/books/0309096537/html.

Appropriate institutional review committee approval must be stated in the Materials and Methods section for human or animal subjects involved in experimental investigations. This statement should also show that informed consent was obtained for human subjects. Such manuscripts must include a statement verifying that the human investigations were preceded by local institutional review board approval and, if appropriate, in accordance with an assurance filed with and approved by the U.S. Department of Health and Human Services.

Recombinant DNA Research Guidelines

Any recombinant DNA research must follow the National Institutes of Health Guidelines for Research Involving Recombinant DNA Molecules (available at http://oba.od.nih.gov/rdna/nih_guidelines_oba.html) and should be described within the manuscript.

Data Sharing

STEM CELLS supports the efforts of the National Academy of Sciences (NAS) to encourage the open sharing of publication-related data. STEM CELLS  adheres to the beliefs that authors should include in their publications the data, algorithms, or other information that is central or integral to the publication, or make it freely and readily accessible; use public repositories for data whenever possible; and make patented material available under a license for research use. For more information, see the NAS website (http://books.nap.edu/books/0309088593/html/1.html).

Distribution of Reagents

The Editors of STEM CELLS follow the policy that any readily renewable resources mentioned in a Journal article not already obtainable from commercial sources shall be made available to all qualified investigators in the field. The policy stems from the long-standing scientific principle that authenticity requires reproducibility. Publication in STEM CELLS constitutes a de facto acceptance of this policy. Included are reagents that can be easily provided—specifically, nucleic acid sequences, cDNA and genomic clones, cell lines, and monoclonal antibody clones. Small amounts (sufficient for the replication of any in vitro work reported) of novel protein reagents are also considered easily transferable.

Although the Editors appreciate that many of the reagents mentioned in STEM CELLS are proprietary or unique, neither condition is considered adequate grounds for deviation from this policy. Suitable material transfer agreements can be drawn up between the provider and requester, but if a reasonable request is turned down and submitted to the Editor, the corresponding author will be held accountable. The consequence for noncompliance is simple: the corresponding author will not publish in STEM CELLS  for the following three years.

Submission of Sequences to GenBank

Original DNA sequences reported in STEM CELLS must also be submitted to GenBank. Instructions for submission can be found at the following address: http://www.ncbi.nlm.nih.gov/Genbank/. An accession number should be supplied parenthetically at a relevant location in text.

STEM CELLS supports the efforts of the Microarray Gene Expression Data Society to standardize the presentation of microarray data. The Journal requires that microarray data be deposited in either the Gene Expression Omnibus (GEO) at http://www.ncbi.nlm.nih.gov/geo/, or in Array Express at http://www.ebi.ac.uk/arrayexpress/.

In your STEM CELLS submission, the accession number and the complete website link for this deposit must be listed in the figure legends or supplemental figure legends of your manuscript, as the Journal will no longer accept for review microarray data that are submitted as figures or files.

Clinical Trials Registry

In accordance with the guidelines published by ICMJE, STEM CELLS will require, as a condition of consideration for publication, that all clinical trials be registered in a public trials registry (for example, at http://www.clinicaltrials.gov). For more information, go to http://www.icmje.org and see Section III.J (Obligation to Register Clinical Trials).

Authors must comply with published CONSORT guidelines (http://www.consort-statement.org/).

The completed checklist must be provided to AlphaMed Press along with the manuscript submitted. The recommended trial flow diagram should be presented as a figure.

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Peer-Review Process

STEM CELLS abides by policy of anonymous peer review. Because this is a single-blind review process, authors do not know the identity of their reviewers. The Editor and Associate Editors appoint Editorial Board members to lead the reviews and select external reviewers from a database of experts. These reviewers provide comments for the Editors and the authors, as well as a publication recommendation. Upon receiving the comments, the Lead Reviewer responsible for the manuscript makes a recommendation to the Editor, who issues the final manuscript decision. Often, the Editors seek manuscript opinions from one another and/or discuss decisions.

Acceptance of manuscripts is based on originality and importance to the field, as assessed by the Editors. Acceptance and publication decisions are made by the Editors.

Based on editorial judgment, some submissions are rejected initially without external review. If review is required, authors may expect to learn of rejection or acceptance in approximately four to five weeks.

Upon completion of review, the Editors' decision will be e-mailed to the contact author, along with the reviewers' comments.

The author will receive one of the following decisions:

  • Reject: The Editors did not select your manuscript for publication. Many factors contribute to acceptance including, but not limited to, the following:
    • Importance of the research to the field
    • Originality of the work
    • Quality of the study
    • Priority of the work to STEM CELLS and its readership

    If an author disagrees with the editorial decision, cordial inquiry is invited. The response must be timely and include a detailed rebuttal.

  • Major Revision: The Editors believe that your article contains information of potential importance but a number of major issues were raised. If you believe that you can address the issues raised, the editors would be willing to reconsider your manuscript, but cannot guarantee acceptance, particularly if you cannot address the concerns.

  • Minor Revision: The Editors found your manuscript potentially acceptable for publication provided you make some minor adjustments.

  • Acceptance: The Editors selected your manuscript for publication. Additional information will be provided regarding embargo policies and the production process.

Authors are given three months to complete a request for major revision and three weeks to complete minor revisions or revisions on a revised manuscript.

For further information, see the "Uniform Requirements for Manuscripts Submitted to Biomedical Journals," published by the International Committee of Medical Journal Editors (ICMJE)

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Manuscript Types

Quick Reference Table:

Original Research Articles

Reports new findings of major importance. The manuscript should include an Abstract, Introduction, Methods, Results, and a Discussion and Conclusion that place the findings in context and examines the implications for future research.

Word limit: 5,000
Display items: 7
Max References: 100
Submission Fee: $90
Publication Fee: $2000
Concise Reviews

Reviews should address the impact of new concepts or information on clinical disease management, including prognosis, treatment, prevention, or diagnosis.

Word limit: 4,000
Display items: 4
Max References: 80
Submission Fee: $90
Publication Fee: $2000
Brief Reports

Short reports of current research. The manuscript should include an Abstract, Introduction, Methods, Results, and a Discussion and Conclusion that place the findings in context and examines the implications for future research.

Word limit: 1,200
Display items: 4
Max References: 25
Submission Fee: $90
Publication Fee: $2000
Letters to the Editor

Letters to the Editor may deal with material in published papers, or they may raise new issues.

Word limit: 500
Display items: 1
Max References: 10
Submission Fee: N/A
Publication Fee: N/A

All accepted articles, excepting invited content and Letters to the Editor, are subject to submission and publication fees as elaborated in the chart above. Authors opting for OnlineOpen will be subject to an additional Gold Open Access fee as described in “Post-Acceptance Information” below.

Original Research Articles

Original Research Articles should meet the following criteria:

  • The manuscript should include an Abstract, informative Introduction, clearly stated Materials and Methods, a succinct presentation of Results, and a Discussion that places the findings in context and examines the implications for science, clinical, and translational medicine disease management. 
  • Total word count (excluding the abstract, references, and text for figures and tables) should not exceed 5,000 words.
  • Abstracts, which are limited to a maximum of 250 words, should clearly state the manuscript's primary objective, discuss the implications of the work, and summarize any conclusions.
  • Total number of figures and tables should not exceed seven (any additional figures and/or tables should be labeled as "supplemental" and will appear online only).
  • A CONSORT diagram is required for all Randomized and Phase III trials (the diagram does not count toward the seven figure and table limit).

For manuscripts involving clinical trials the manuscript also must include:

  • The trial registry and registration identification number for the trial's registry is required. This applies to any trial for which patient enrollment began on or after November 1, 2006.
  • Any study related protocol information for all randomized clinical trials.
  • Negative results from clinical trials important to the field but often underreported are encouraged.
  • Clear statement and approval from the ethical committee and others when animal or human material has been used
  • The majority of the manuscript text, excluding the abstract and introduction, should present new data and discussion that address the impact of new concepts or information on clinical and translational medicine disease management.

References should not exceed 100 entries and should be limited to recent works.

Concise Review Articles

STEM CELLS encourages concise manuscripts that document significant advances made through novel technology developments. These papers should be submitted to the appropriate Journal section.

While the majority of Concise Reviews are solicited by the Editors, STEM CELLS also welcomes unsolicited reviews that address topics of significant interest and relevance to the translational aspects of stem cells and progenitor cells for cell-based therapy, tissue engineering, and regenerative medicine from the bench to patient care.

Prior to submitting an unsolicited manuscript, authors are asked to review published reviews on the same topic in other widely read publications.

Authors should submit a pre-submission inquiry to Editors@StemCells.com. We will review manuscripts submitted by academic, government, or industry authors, but not medical writers or other paid representatives. All authors should be identified in the pre-submission inquiry. The author should explain in the pre-submission inquiry what new information or perspective justifies the manuscript as a candidate for publication in STEM CELLS. The inquiry must also:

  • Provide a detailed description of the primary concepts and discoveries addressed in the manuscript and discuss recent reviews on the same topic in related publications
  • List specific clinical trials, if pertinent, to be discussed in the manuscript
  • Disclose any potential conflict of interests for all authors

Concise Review articles should meet the following criteria:

  • Total word count (excluding the abstract, references, and text for figures and tables) should not exceed 3,000 words.
  • Abstracts, which are limited to a maximum of 250 words, should be a cutting edge review of the subject setting them apart from other sources of information and clearly state the manuscript’s primary objective, discuss the implications of the work, and summarize any conclusions.
  • The majority of the manuscript text, excluding the abstract and introduction, should address the impact of new concepts or information on clinical disease management, including prognosis, treatment, prevention, or diagnosis.
  • The review should detail how the authors planned the review of the literature, what information was included or excluded, whether levels of evidence were used in assessing the value of each publication selected for inclusion, and whether unpublished material was included.
  • Opinions not supported by clear evidence should be identified as such and properly discussed.
  • Total number of figures/graphics and tables should not exceed two (any additional figures and/or tables should be labeled as supplemental and will appear online only).
  • References should not exceed 50 and be limited to recent works. The authors may also include previous high-quality reviews that summarize earlier work on the subject of the review.

Brief Reports

Brief Reports should be no more than 1,200 words (excluding abstract, tables, figures, legends and references), and a maximum total of four figures and/or tables combined.

Letters to the Editor

Letters to the Editor are welcomed. They may deal with material in published papers, or they may raise new issues. Letters should be no more than 500 words (excluding abstract, tables, figures, legends, and references), and one figure and/or table is allowed. Authors of papers referenced in Letters to the Editor are given the opportunity to respond. Both the letter and the response are subject to peer review.

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Formatting Your Manuscript

Language

Papers are published in English (with American spellings), and authors who are not fluent in this language must seek editorial help before submitting their papers. Papers that do not meet basic standards for readability may not be considered for review, although lack of fluency with English is rarely the primary reason for rejection of a manuscript.

Companies that provide substantive editing after the authors draft a first version, including the following:

http://www.aje.com/
https://www.editage.com/
http://www.bioedit.co.uk
http://www.biosciencewriters.com
http://www.bostonbioedit.com
http://www.prof-editing.com
http://www.stallardediting.com
http://www.bluepencilscience.com

The Journal takes no responsibility for, nor endorses, these services. Their use does not guarantee acceptance of a manuscript for publication. Use of any editorial service must be noted in the Acknowledgment section, as well as any support provided for these services.

Submission Cover Letter

Submissions should be accompanied by a cover letter briefly describing the work’s significance and identifying the corresponding author, with:

  • complete mailing address
  • telephone and fax numbers
  • e-mail address

Title Page

The first page of the manuscript should contain the following information:

  • the title, which should be concise and descriptive, no more than 150 characters in length
  • a running head of the title that is no more than 50 characters, including spaces
  • name(s) of author(s)
  • name(s) of institution(s) at which the work was done
  • author contributions:

    Each author's contribution(s) to the manuscript must be indicated according to the categories listed below:

    1. Conception and design
    2. Financial support
    3. Administrative support
    4. Provision of study material or patients
    5. Collection and/or assembly of data
    6. Data analysis and interpretation
    7. Manuscript writing
    8. Final approval of manuscript
    9. Other (please be specific)

Please use the following format when adding this information to your title page:
John Doe: Conception and design, financial support, manuscript writing
Jane Doe: Conception and design, provision of study material or patients

Please refer to the Journal's policy on authorship and contributions for more information.

  • correspondence information for corresponding author (name, degree, address [including postal code], telephone and fax numbers, and e-mail address)
  • disclaimers, if any
  • a brief acknowledgment of grants, equipment, or drugs for research support
  • four to six key words or phrases, using terms from the most recent Medical Subject Headings of National Center of Biotechnology information (http://www.nlm.nih.gov/mesh/)

Search Engine Optimization (SEO)

Although all published articles are accessible online, authors can take steps to improve their article's online discoverability. Search engine optimization (SEO) techniques can help boost STEM CELLS content to high-ranking positions in search results, resulting in greater visibility, readership, and citations for your article.

Key techniques you can use to improve your article's SEO are:

  • Carefully select at least 5 relevant key words
  • Lead with key words in the article title
  • Repeat key words 3-4 times throughout the abstract
  • Link to the published article on social media, blogs, and academic websites

Because they are highly utilized by search engines when ranking search results, selecting appropriate key words (i.e., search terms) and using them frequently and appropriately in the title, abstract, and article is critical.

Abstract

An abstract is required for all Original Research Articles, Concise Reviews, and Brief Reports. The abstract should:

  • contain no more than 250 words
  • clearly state the paper's primary objective
  • if appropriate, describe materials and methods and results
  • discuss the implications of the work
  • summarize any conclusions
  • be readable by non-specialists as well as experts in the field
  • define abbreviations and acronyms on first usage

The abstract should not contain:

  • footnotes
  • statistical significance values
  • references
  • proprietary names

Graphical Abstract

A graphical abstract is a visual representation of the key concepts in the article. Authors are invited to upload an attractive full-color, high-quality graphic that illustrates the important findings of their research. These are often the concluding figure from the article or a figure that is specially designed to give readers a preliminary understanding of the manuscript while browsing. The graphical abstract should be submitted in .eps or .tif format, preferably at the time of manuscript submission, and should be accompanied by a short (150 word) caption. The graphical abstract will be printed square with sides 2 inches/5 cm; the use of graphs and images consisting of several parts or panels is therefore strongly discouraged.

Text

The text should be divided into the following sections (when appropriate) and in the following order:

  • Introduction
  • Materials and Methods
  • Results
  • Discussion
  • Conclusion and/or Summary
  • Acknowledgments
  • Disclosure of Potential Conflicts of Interest
  • References
  • Figure legends
  • Tables
  • Figures

Within the text:

  • Acronyms, abbreviations, and symbols must be clearly defined on first usage
  • Footnotes are not allowed, except within tables
  • References, tables, and figures must be numbered in the order in which they are cited in the text

All submitted material should be typed double-spaced, leaving left and right margins of at least 2.5 cm. Do not justify the right-hand margin. Number the pages consecutively.

Notes on Style

STEM CELLS follows the style of the American Medical Association (Manual of Style: A Guide for Authors and Editors, 10th ed. [2007]). Please refer to the style book when preparing your manuscript. Some particular notes on style are included below.

Units of Measurement

  • Measurements of length, weight, and volume should be reported in metric units (meter, kilogram, or liter) or their decimal multiples.
  • Temperatures should be given in degrees Celsius.
  • Abbreviations for units of measurement need not be defined (e.g., 5 cm, 20°C, 120 mmHg).

Symbols and Abbreviations

Define abbreviations and acronyms the first time used, both in the abstract and in the body of the article. Author-created abbreviations should be avoided, but if used they must be clearly defined at first usage, both in the abstract and in the paper.

Footnotes

Footnotes should not be used except within tables.

References

References must be numbered consecutively, without periods after the reference numbers, and ordered as they appear in the text (i.e., citation by number). References must be typed double-spaced in a separate reference section that follows the body of the text. Manuscripts “in preparation” or “submitted” are not included in the reference list but instead are placed in parentheses in the text. However, articles that have been accepted for publication by a journal should be listed in the reference list as “in press.”

Reference format:

  • List all authors when there are three or fewer.
  • If there are more than three authors, list the first three followed by "et al."
  • List authors by last name first, followed by their initials (no periods).
  • Abbreviations for titles of medical periodicals should conform to those in MEDLINE journal abbreviations
  • Use full beginning and ending page numbers (e.g., 10270–280 is not acceptable).

Examples of references:

  • Standard journal article
    1 Rasheed Z, Kowalski J, Smith BD et al. Concise review: Emerging concepts in clinical targeting of cancer stem cells. Mol Endocrinol 2011;29:883–887.
  • Article in journal supplement
    2 Stewart D. Topotecan in the first-line treatment of small cell lung cancer. Am J Med 2004;9(suppl 6):33–42.
  • Journal article, in press
    3 Prat A, Perou CM. Deconstructing the molecular portraits of breast cancer. Mol Oncol 2010 (in press).
  • Book
    4 Atala A, Lanza R, Thomson J. Principles of Regenerative Medicine. 2nd ed. Waltham, MA: Academic Press, 2010.
  • Chapter in a book
    5 Clark J. Molecular targeted drugs. In: Chabner B, Longo D, eds. Cancer Chemotherapy and Biotherapy: Principles and Practice. 5th ed. Philadelphia, PA: Lippincott Williams & Wilkins, 2010:526–546.
  • Abstract
    6 Hauschild A, Eggermont AM, Jacobson E et al. Phase III, randomized, double-blind study of elesclomol and paclitaxel versus paclitaxel alone in stage IV metastatic melanoma (MM). J Clin Oncol 2009;27(suppl 18): Abstract LBA9012.
  • Letter to the Editor
    7 Welsh J. Contagious cancer [letter]. Proc Natl Acad Sci USA 2011:16:1–4.
  • Internet resource
    8 U.S. National Institutes of Health. Efficacy and safety study of OncoV-EXGM-CSF compared to GM-CSF in melanoma. Available at http://clinicaltrials.gov/ct2/show/NCT00769704. Accessed June 11, 2010.
  • E-only Journals with digital object identifier
    9 Nefzger C, Haynes J Pouton C. Directed expression of Gata2, Mash1, and Foxa2 synergize to induce the serotonergic neuron phenotype during in vitro differentiation of embryonic stem cells. STEM CELLS 10.1002/stem. 2011-640.
  • E-Pub Ahead of Print
    10 Trent B, Manning P, Hastings E et al. A new wrinkle in the ethics of pharmacological research. Pharm Res 2005 [Epub ahead of print].
  • Theses/Dissertations
    11 Mattingly D. The Science of Language [master's thesis]. Athens, GA: The University of Georgia; 2003.

    Proceedings/Meeting Reports/Conference Presentations:

    • Unpublished:
      12 Bird L. Market forces and physician workplace reform. Paper presented at: Annual Meeting of the Association of American Medical Colleges; November 24, 1996; Wilmington, NC. 
    • Published:
      13 Slama K, ed. Tobacco and Health: Proceedings of the Ninth World Conference on Tobacco and Health, Paris, France, 10-14 October 1994. New York, NY: Plenum Press; 1995.
  • Foreign Language Titles Translated into English:
    14 Salmon RJ, Vilcoq JR. Breast cancer after preventive subcutaneous mammectomy [in French]. Presse Med 1995;24:1167–1168.

Tables

Tables must be titled and cited in numerical order in the text using Arabic numbers. Each table should be double-spaced and typed on a separate page. Use superscript lowercase letters to denote footnotes within a table in the order they appear. Each table must include definitions of all abbreviations used in it. Tables should be created in Microsoft Word using the table feature. Tables must not be embedded within the manuscript but should be submitted as individual files in .doc format and designated as “figures” during the submission process. Failure to comply with these specifications may result in review delay.

Figures

Figures must be titled and cited in numerical order in the text using Arabic numbers. We encourage the submission of illustrations in color when they enhance the presentation of the data. Authors incur no additional charges for the publication of figures in color. Figures should be submitted as individual files and designated as “figures” during the submission process. Figures should be labeled with the Corresponding Author name, the appropriate figure number, and orientation (e.g., “top”). Figures may be submitted as multipart panels.

Acceptable Formats

Figures should be submitted in either .tif or .eps format. All other file types, such as Excel spreadsheets and PowerPoint presentations, are not accepted for review. Failure to comply with these specifications may result in review delay.

Size

Submit figures at their final publication size; do not scale figures. Prepare figures at 1-column width or, if necessary, 1½ column width. The 2-column width should not be used unless necessary.

Columns

Inches

Centimeters

Picas

1

3.2

8.2

19.25

1.5

4.5

11.4

27

2

5.8

14.8

35

The height of all figures must be less than or equal to 9.6" / 24.5 cm / 58 picas.

Figure text

Please use Calibri font for all figure text. Multipanel figures should be labeled using uppercase 12-point Calibri Bold. If Calibri font is not available, substitute a similar sans serif font, such as Arial or Helvetica. All text and numbers on a figure, including scale bars and axis labels, must be large and clear enough to be legible when printed. A minimum text size of 6 points is recommended.

Line and bar graphs

Lines in graphs should be bold enough to be easily read after reduction, as should all symbols used in the figure. Line or bar graphs or flow charts with text should be created in black and white, not shades of gray, which are difficult to reproduce in even tones. If more than two sets of data are represented, use of fill patterns or colors (not gray) is suggested to present the data clearly.

Figure brightness

Please make sure that images are sufficiently bright and high-contrast for detail to show up well when printed. Images that are too dark may require replacement.

Resolution

Minimum resolution is 300 dpi for color and grayscale figures, 600 dpi for combination halftones, and 1000 dpi for line art.

Image Integrity

No specific feature within an image may be enhanced, obscured, moved, removed, or introduced.

Adjustments of brightness, contrast, or color balance are acceptable if they are applied to the whole image and as long as they do not obscure, eliminate, or misrepresent any information present in the original. The grouping of images from different parts of the same gel, or from different gels, fields, or exposures must be made explicit by the arrangement of the figure (e.g., dividing lines) and in the text of the figure legend. If the original data cannot be produced when requested, the acceptance of the manuscript may be revoked.

Figure Legends

Figure legends, including those for supplemental figures, should be included in the manuscript after the references. They should be typed double-spaced and contain a brief title and explanation of the figures (maximum of 250 words for title and explanation). In addition, the magnification and stain used for photomicrographs should be stated, scale bars should be included if necessary, and any pertinent notes and definitions of all abbreviations used in the figure must be included.

Permission

Authors must obtain permission if required for reproduction or adaptation of figures or tables from copyrighted (previously published) material. Written permission must be obtained from the publisher of the journal or book concerned and included with the manuscript submission.

The publication from which the figure or table is taken must be listed in the reference section. The following should appear within the legend of a reprinted table or figure: “Reprinted with permission” along with the appropriate reference. All permission listings must be shown in the submitted manuscript; they cannot be entered on proofs.

Permissions Information form

Supplemental Data

The submission of supplemental data that enhance the understanding of the science discussed in the manuscript is encouraged. Supplemental data should be submitted for peer review when the initial submission of the paper occurs. Supplemental materials should be submitted as a single text document, supplemental figures as individual .tif or .eps file, supplemental tables as a single Word document or Excel file. The Editors will review the supplemental data along with the manuscript. Critical information or figures required for the interpretation, understanding, and evaluation of the research must be included in the manuscript and must not be submitted as supplemental data. Supplemental data are published online only and are not copyedited prior to publication.

Videos

Videos for use on the Journal’s website are subject to editorial approval and should be uploaded online with your manuscript files. The preferred file format is compressed Windows Media Player-compatible (.wmp or .mpg). Video file size should be kept as small as possible while maintaining good resolution and screen size. Video files submitted to STEM CELLS are posted online only as supplemental data. Within the text of your manuscript, you may cite the videos as, for example, “supplemental online Video 1.” Prior to including a video in your submission, please read the Supplemental Data section above.

Video Highlight

STEM CELLS features Video Highlights on the Journal homepage for published manuscripts. Authors of accepted articles are welcome to submit a short (2-5 minute) video abstract to discuss the key concepts of their research. The preferred file format is compressed Windows Media Player-compatible (.wmp or .mpg). Video file size should be kept as small as possible while maintaining good audio, resolution and screen size. Video Highlights are subject to editorial review and will be tagged with keywords, a description, and a link to the article.

This video supplement will add a new dimension to the work and is intended to draw additional readers. Authors may create their own Video Highlight or, alternatively, our partners at Research Square offer a service of professionally produced video abstracts. You can learn more about it, and purchase one for your article, at https://www.researchsquare.com/wiley. If you have any questions about this service, please direct them to videoabstracts@wiley.com.

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Preparation And Online Submission Of Articles

General Instructions for Online Manuscript Submission

Formats

All manuscripts should be submitted in Microsoft Word format (.doc or .docx extension). All tables should be created in Microsoft Word using the table feature. All figures should be in .tif or .eps format. This applies to both Windows and Macintosh platforms. Files submitted in any other format may incur errors during the peer review process. Other file types, including Excel spreadsheets and PowerPoint presentations, are not recommended. Failure to comply with these specifications may result in review delay.

Fonts

Times New Roman provides optimum readability; however, other acceptable fonts are Arial, Courier, Helvetica and Times.


Submitting a Manuscript

To submit manuscripts, authors should log in to Manuscript Central, http://mc.manuscriptcentral.com/stemcells

For technical assistance in uploading your manuscript files, please refer to the “Help” button in Manuscript Central to access the Author User Guide. If there are any other questions regarding the submission steps, please feel free to contact the Editorial Office or ScholarOne for support.

Submission Fee

A nonrefundable submission fee of $90 USD is required upon online submission of the manuscript. ScholarOne Manuscripts is integrated with PayPal to make this transaction easier. Please make payment in U.S. funds with a credit card (American Express, MasterCard, or Visa).


Financial Disclosure/Conflict of Interest Form

For the initial submission, the corresponding author must complete and sign the Potential Conflict of Interest and Financial Disclosure Form. These should be uploaded with the manuscript files at the time of submission.

Please be aware that Manuscript Central will send all communications about the paper (including the request for final approval and the confirmation of submission) to the submitting author, unless otherwise noted.

Submission of Revised Manuscripts

In addition to the sections described above, revised manuscripts must also contain a detailed point-by-point response to the comments of the reviewers and/or editors. The cover letter should briefly summarize how the revised manuscript addressed these comments.

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Post-Acceptance Information

Page Proofs

The corresponding authors are sent page proofs, which are to be carefully proofread for any copyediting or typesetting errors. Authors should also make sure that any renumbered tables, figures or references match text citations and that figure legends correspond with text citations and actual figures. Please also make sure that author names and institutions are correct on the title page. Any corrections made at the page-proof stage will be applied to the publish-ahead-of-print version of the manuscript online and to the printed version of the manuscript. Proofs must be returned within 48 hours of receipt.

Embargo

Materials submitted to STEM CELLS are embargoed for release until 2 p.m. Eastern U.S. time on the day before the mailing date (for the print edition) or the date when the article is posted online, whichever comes first. This policy applies to members of the media, authors, institutions' public information officers, and the public. Authors may not discuss their work with the media until 1 week before the mailing date or 1 week before online posting of the article, whichever is earlier, and must ensure that the media representatives agree to abide by the embargo policy. STEM CELLS may refuse to publish a manuscript, despite acceptance for publication, if it has been prematurely released to the press.

In order to schedule a planned institutional press release for an accepted article, please coordinate with the Editorial Office upon acceptance.

Publication Fee (Required Fee)

Proffered manuscripts that are accepted for publication will be assessed a publication fee of $2,000, which includes all page charges and any applicable color charges. The author agrees to pay this fee within 30 days of receiving the co-publisher's invoice. If an author is unable to support this publication fee, it is his or her responsibility to inform the Editorial Office at the time of manuscript submission. Letters to the Editor and invited manuscripts are exempt from the publication fee.

OnlineOpen (Optional Fee)

OnlineOpen is available to authors of primary research articles who wish to make their article freely available immediately after publication to non-subscribers on the STEM CELLS website. This option provides support to authors who wish or need to sponsor open access, or whose funding agency requires grantees to archive the final version of their article. With OnlineOpen, the author, the author's funding agency, or the author's institution pays a $2,000 fee to ensure that the article is made available to non-subscribers upon publication via Wiley Online Library, as well as deposited in the funding agency's preferred archive. The open access option will be made available to authors only after peer-review and editorial acceptance of their articles for publication in order to prevent any potential conflicts of interest.

For the full list of terms and conditions, see http://wileyonlinelibrary.com/onlineopen#OnlineOpen_Terms.

Any authors wishing to send their paper OnlineOpen will be required to complete the payment form available from our website at: https://authorservices.wiley.com/bauthor/onlineopen_order.asp. Prior to acceptance there is no requirement to inform an Editorial Office that you intend to publish your paper OnlineOpen if you do not wish to. All OnlineOpen articles are treated in the same way as any other article. They go through the journal's standard peer-review process and will be accepted or rejected based on their own merit.

Copyright Transfer Agreement

Manuscripts will not be published until each author has completed a copyright transfer agreement with both co-publishers. If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an e-mail from the Publisher prompting them to login into Author Service; where via the Wiley Author Licensing Service (WALS) they will be able to complete the license agreement on behalf of all authors on the paper.

For authors signing the copyright transfer agreement:

If the OnlineOpen option is not selected the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with the Copyright FAQs below:

CTA Terms and Conditions:http://exchanges.wiley.com/authors/faqs---copyright-_301.html

For authors choosing OnlineOpen:

If the OnlineOpen option is selected the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):

  • Creative Commons Attribution Non-Commercial License OAA
  • Creative Commons Attribution Non-Commercial -NoDerivs License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services http://exchanges.wiley.com/authors/faqs---copyright-_301.html and visit http://www.wileyopenaccess.com/details/content/12f25db4c87/Copyright--License.html.

If you select the OnlineOpen option and your research is funded by certain funders [e.g. The Welcome Trust and members of the Research Councils UK (RCUK) or the Austrian Science Fund (FWF)] you will be given the opportunity to publish your article under a CC-BY license supporting you in complying your Funder requirements . For more information on this policy and the Journal’s compliant self-archiving policy please visit: http://www.wiley.com/go/funderstatement

For RCUK, Welcome Trust, FWF authors click on the link below to preview the terms and conditions of this license:
Creative Commons Attribution License OAA

To preview the terms and conditions of these open access agreements please visit the Copyright FAQs hosted on Wiley Author Services http://exchanges.wiley.com/authors/faqs---copyright-_301.html and visit http://www.wileyopenaccess.com/details/content/12f25db4c87/Copyright--License.html.

NIH Public Access Mandate

The co-publishers will support our authors by posting the accepted version of articles by NIH grant-holders to PubMed Central upon acceptance by the Journal. The accepted version is the version that incorporates all amendments made during peer review, but prior to the publisher’s copy-editing and typesetting. This accepted version will be made publicly available 12 months after publication. The NIH mandate applies to all articles based on research that has been wholly or partially funded by the NIH and that are accepted for publication on or after April 7, 2008.

NIH authors should be aware that they will receive an e-mail request once Wiley has posted the files of their accepted manuscript to the NIH Manuscript Submission system to approve the upload for display on the PubMed Central system. Without the author’s active consent the file upload to PubMed Central will not be completed. This is a requirement of their grant/affiliation.

For NIH employees only, we will accept the NIH Publishing Agreement.

Welcome Trust-Funded Articles

Since October 1, 2006, Welcome Trust grantees are required to submit an electronic copy of the final manuscripts of their research papers to PMC or UKPubMed Central (UKPMC). The Welcome Trust requires that the author’s work be made available to the public via PMC and PMC mirror sites no later than six months after final publication. The co-publishers have established a policy that will allow authors who publish in STEM CELLS to comply with these requirements.

The co-publishers authorize Welcome Trust-funded authors whose papers are accepted and published in STEM CELLS permission to deposit the author’s peer-reviewed manuscript (but not published format) in PMC and UKPMC no earlier than six months after the print publication in STEM CELLS. Additionally, the author is authorized to replace the peer-reviewed author manuscript with the final published version 12 months after print publication in STEM CELLS. Further information on the Welcome Trust policy is available at: http://www.wellcome.ac.uk/node3302.html.

Howard Hughes Medical Institute (HHMI)-Funded Articles

The Institute's policy on public access to publications takes effect for manuscripts submitted for publication on or after January 1, 2008, for which an HHMI scientist is a major author. HHMI has designated PubMed Central (PMC) as the repository for journals in the biological sciences.

The co-publishers facilitate the deposit of HHMI-funded articles into PMC and also makes them publicly available online within six months of publication. Further information on the HHMI policy is available at http://www.hhmi.org/about/research/policies.html.

Author Rights

As an author, you are granted rights for a large number of author uses, including use by your employer (institution or company). These rights are granted and permitted without the need to obtain specific permission from the copyright holder, AlphaMed Press, provided a full credit line is prominently placed [i.e., author name(s), journal name, copyright year, volume number, inclusive pages, and copyright holder]. These author rights are granted and apply only to articles for which you are named as the author or co-author. The author rights include:

  • the right to make copies of the article for your own personal use, including for your own classroom teaching use;
  • the right to make copies and distribute copies (including via e-mail) of the article to research colleagues, for the personal use by such colleagues (but not commercially or systematically, e.g., via an e-mail list or listserv);
  • the right to present the article at a meeting or conference and to distribute copies of such paper or article to the delegates attending the meeting;
  • for the author’s employer, if the article is a “work for hire,” made within the scope of the author’s employment, the right to use all or part of the information in (any version of) the article for other intracompany use (e.g., training);
  • patent and trademark rights and rights to any process or procedure described in the article;
  • the right to include the article in full or in part in a thesis or dissertation (provided that this is not to be published commercially);
  • the right to use the article or any part thereof in a printed compilation of works of the author, such as collected writings or lecture notes (subsequent to publication of the article in the Journal);
  • the right to prepare other derivative works, to extend the article into book-length form, or to otherwise reuse portions or excerpts in other works, with full acknowledgment of its original publication in the Journal; and
  • the right to self-archive the work by posting the work as the final peer-reviewed author’s manuscript (but not published layout) on his/her own website and his/her institution’s website and repository no earlier than six months after print publication in STEM CELLS provided that a link is made to the AlphaMed Press version.

Communication Among Scientists or Clinical Investigators

STEM CELLS does not wish to hinder communication among scientists or clinical investigators. Authors are permitted to discuss their manuscripts with their peers and to present their work to their peers at professional conferences. However, authors should not discuss or distribute any portion of an unpublished manuscript in a manner that may intentionally or inadvertently lead to the distribution of the material to the media or general public. Manuscript material may be projected onto a screen for viewing, but no handouts or photocopies of article proofs or preprints may be disseminated. Furthermore, we ask that comments to the media do not elaborate upon the content of your presentation. Finally, please inform STEM CELLS that you are planning to make such a presentation.

Corrections to Published Articles

If you believe a correction is needed to a published article, please send an e-mail to EditorialOffice@stemcells.com. Please include the full citation of the article, location of the error, and if possible, suggest the correction.

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Reprints and Permissions

STEM CELLS can publish borrowed material only with written permission of the original publisher. If you use illustrations and tables in your manuscript that are obtained from other sources, you must obtain permission from the original source for each. Secure these permissions as soon as possible. To assist you in this process, click here for a helpful checklist to follow for each permission required.

Copyright Notice

STEM CELLS® (pISSN 1066-5099) and STEM CELLS Online (eISSN-1549-4918) and all contributions included therein are protected by copyright. All rights are reserved under United States and international copyright laws and other applicable laws and conventions. No copyright is claimed in any original work created by agencies or employees of the United States government.

No part of this publication may be reproduced or transmitted in any form without the prior written consent of AlphaMed Press or Copyright Clearance Center. Certain provisions of the Copyright Act of 1976, as amended, respecting fair use and reproduction by libraries and archives, 17 U.S.C. §§ 107 and 108, may be applicable.

Reprints

Reprints may be purchased at https://caesar.sheridan.com/reprints/redir.php?pub=10089&acro=stem.

Permissions

Procedure to Request Permission

Permission requests, as described below, to photocopy, distribute, and republish material from STEM CELLS should be directed to the Copyright Clearance Center (CCC):

  • Classroom handouts
  • Print and electronic coursepacks
  • Interlibrary loan
  • Library reserves
  • Business purposes (sharing information with investors, prospects, clients, and partners)
  • Republish figures, tables, abstracts, or excerpts in another book, journal, or newsletter
  • Republish figures, tables, abstracts, or excerpts in a brochure or pamphlet
  • Use of figures, tables, abstracts, or excerpts in PowerPoint
  • Use of figures, tables, abstracts, or excerpts in a dissertation or thesis paper

The CCC will grant requests only to reproduce our material exactly as it was originally published. You can submit your request to the CCC via traditional mail, fax, or e-mail. Additionally, you can secure permission online using their automated online system. Submit requests to:
Traditional mail: CCC, 222 Rosewood Drive, Danvers, Massachusetts 01923, USA
Telephone: 978-750-8400 (8:00 am-5:30 pm EST)
Fax: 978-646-8600
E-mail: info@copyright.com
Online: www.copyright.com

All other permission requests should be made in writing to the Permissions Department, c/o John Wiley & Sons, Inc., 111 River Street, Hoboken, NJ 07030: (201) 748-6011, fax (201) 748-6008, E-mail: permreq@wiley.com, and should include a statement of intended use, as well as explicit specifications of the materials to be reproduced. When submitting your permission request, please include the following information:

  • A complete citation of the requested material (title of journal, volume number, issue number, year, author name, article title, specific page numbers)
  • The intended use of the material (for publication, slides, handouts, etc.)
  • If for handouts: the number of copies being made
  • If for republication: the publisher and the name of the new publication
  • How the material will be reproduced and distributed
  • Complete contact details (name, institution/company name, address, telephone, fax, e-mail)

Internet sites interested in linking to information published by John Wiley & Sons must submit a written request and include the following information: Originating website URL, company business focus, complete contact information, and description of the specific page or material to be linked.

Contact Information

Request assistance with online submission and inquire about the status of submitted papers at: EditorialOffice@StemCells.com

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Video abstract from Dr. Dunaway et al. on his recently published STEM CELLS paper entitled, "Dental Pulp Stem Cells Model Early Life and Imprinted DNA Methylation Patterns." Read the paper here.

Video abstract from Dr. Hochane et al. on his recently published STEM CELLS paper entitled, "Low-Dose Pesticide Mixture Induces Senescence in Normal Mesenchymal Stem Cells (MSC) and Promotes Tumorigenic Phenotype in Premalignant MSC." Read the paper here.

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