Aims and Scope


STEM CELLS, a peer reviewed journal published monthly, provides a forum for prompt publication of original investigative papers and concise reviews. STEM CELLS is read and written by clinical and basic scientists whose expertise encompasses the rapidly expanding fields of stem and progenitor cell biology. STEM CELLS welcomes original articles and concise reviews describing basic laboratory investigations of stem cells and the translation of their clinical aspects of characterization and manipulation from the bench to patient care. The Journal covers all aspects of stem cell research including embryonic stem cells/induced pluripotent stem cells; tissue-specific stem cells; stem cell technology: epigenetics, genomics, proteomics, and metabonomics; cancer stem cells; translational and clinical research; and regenerative medicine.


STEM CELLS covers:

Cancer Stem Cells

  • Cellular origin of cancer stem cells
  • Genetic constraints, including epigenetic modifications, that influence growth process
  • The cancer stem cell niche, and cancer stem cells as therapeutic targets
  • Mathematical models of cancer cell evolution and mechanisms of survival

Embryonic Stem Cells/Induced Pluripotent Stem (iPS) Cells

  • Signaling pathways/factors regulating and/or initiating ESC/iPS cells pluripotency and differentiation
  • Derivation and organization of primitive, early structures with or without tissue specificity

Regenerative Medicine

  • Potential applications for stem cell-based strategies in pathological conditions
  • Tissue engineering and characterization of engineered tissues
  • Medical device and artificial organ development
  • Stem cell transplantation and technologies that will maintain, improve or restore the function of diseased organs
  • Gene therapies for inherited diseases

Stem Cell Technology: Epigenetics, Genomics, Proteomics, and Metabonomics

  • Mutagenesis and epigenetic influences
  • Surveys of gene and/or protein expression with a link to structure or function
  • Quantitative measurements of the dynamic multiparametric metabolic response of living systems to pathophysiological stimuli or genetic modification
  • Prediction of the outcome (efficacy or toxicity) of a drug or xenobiotic intervention in an individual based on a mathematical model of preintervention metabolite signatures

Tissue-Specific Stem Cells

  • Regulation of and pathways that govern stem cell self-renewal and/or differentiation
  • Cellular interactions and signaling pathways necessary for tissue specificity
  • Molecules and signaling pathways that modulate homing or mobilization of tissue-specific stem/progenitor cells
  • Functional properties of tissue-specific and progenitor cells
  • Improving engraftment for efficient and less costly cellular therapy for adult stem cells
  • Understanding and avoiding teratoma formation

Translational and Clinical Research

  • Studies describing new model systems with potential for drug development
  • Translation into pharmaceutical, clinical or practical findings

Abstracting and Indexing Information

  • Academic OneFile (GALE Cengage)
  • Biological Abstracts (Thomson Reuters)
  • Biological Sciences (ProQuest)
  • BIOSIS Previews (Thomson Reuters)
  • Biotechnology & Bioengineering Abstracts (ProQuest)
  • Biotechnology Research Abstracts (ProQuest)
  • Calcium & Calcified Tissue Abstracts (ProQuest)
  • CAS: Chemical Abstracts Service (ACS)
  • Chemoreception Abstracts (ProQuest)
  • CSA Engineering Research Database (ProQuest)
  • CSA Nucleic Acids Abstracts (ProQuest)
  • CSA Technology Research Database (ProQuest)
  • Current Contents: Life Sciences (Thomson Reuters)
  • Embase (Elsevier)
  • Genetics Abstracts (ProQuest)
  • Health Reference Center Academic (GALE Cengage)
  • HEED: Health Economic Evaluations Database (Wiley-Blackwell)
  • InfoTrac (GALE Cengage)
  • Materials Science & Engineering Database (ProQuest)
  • MEDLINE/PubMed (NLM)
  • Neurosciences Abstracts (ProQuest)
  • ProQuest Biological Science Collection (ProQuest)
  • ProQuest Central (ProQuest)
  • ProQuest Health & Medical Complete (ProQuest)
  • ProQuest Natural Science Collection (ProQuest)
  • ProQuest SciTech Collection (ProQuest)
  • ProQuest Technology Collection (ProQuest)
  • Science Citation Index (Thomson Reuters)
  • SCOPUS (Elsevier)
  • VINITI (All-Russian Institute of Science & Technological Information)
  • Web of Science (Thomson Reuters)

Press Releases

Stem Cells May Help Improve Corneal Wound Healing

Stem Cell Treatment Has Potential to Help Parkinson’s Disease Unexpected Brain Area

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Article Scans

Video Highlights

Video abstract from Drs. Banerjee, Surendran, Bharti, Morishita, Varshney, and Pal on their recently published STEM CELLS paper entitled, "Long non-coding RNA RP11-380D23.2 drives distal-proximal patterning of the lung by regulating PITX2 expression." Read the paper here.

Video abstract from Drs. Sayed, Ospino, Himmati, Lee, Chanda, Mocarski, and Cooke on their recently published STEM CELLS paper entitled, "Retinoic Acid Inducible Gene 1 Protein (RIG1)-like Receptor Pathway is Required for Efficient Nuclear Reprogramming." Read the paper here.

Video Library

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